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New advances in the diagnosis and management of
Oct 26 2020 · Introduction. Over the past decade considerable advances have been made in the surveillance diagnosis and management of hepatocellular carcinoma.1 Despite decreasing incidence rates of the disease disease specific mortality rates remain high 2 and early diagnosis is vital to improving outcomes.3 4 Surveillance of hepatocellular carcinoma is an excellent method to detect the
Get PriceAntibody–Drug Conjugates A Comprehensive Review
Antibody–drug conjugates (ADC) are one of the fastest growing anticancer drugs. This approach comprises a mAb conjugated to the cytotoxic payload via a chemical linker that directed toward a target antigen expressed on the cancer cell surface reducing systemic exposure and therefore toxicity. ADCs are complex molecules that require careful attention to various components.
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A recent survey of the state of EBP in nurses indicated that while nurses had positive attitudes toward EBP and wished to gain more knowledge and skills they still faced significant barriers in employing it in practice. In spite of many significant advances nurses still have more to
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Recent Advances in the Surgical Treatment of Differentiated Thyroid Cancer A Comprehensive Review. Raghunandan Venkat1 and Marlon A. Guerrero 1 2. 1Division of Surgical Oncology Department of Surgery University of Arizona P.O. Box 245131 Tucson AZ USA. 2Division of Surgical Oncology Arizona Cancer Center Tucson AZ 85719 USA.
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Aug 16 2018 · Global developmental delay (GDD) and intellectual disability (ID) affect up to three per cent of the paediatric population .The diagnosis of GDD is limited to children younger than 5 years old but these children often evolve to meet diagnostic criteria for ID and probably represent the same population ().Because the etiological diagnoses of GDD and ID overlap it is natural that
Get PriceAdvances in the management of chronic insomnia The BMJ
Jul 06 2016 · Chronic insomnia is a common condition that affects people worldwide and has negative effects on patients health and wellbeing. The treatment of insomnia can be complex and time consuming for patients and providers. Although behavioral interventions are the first line therapy there are barriers to access for these treatments. However in recent years alternative ways of providing these
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The results of this review will be submitted to a peer-review journal for publication. Conclusion This network meta-analysis will provide a comprehensive review on the most effective treatments for the management of chronic neck pain providing key evidence-based information to patients clinicians and other relevant stakeholders. Registration
Get PriceThe low FODMAP diet recent advances in understanding its
This review aims to present recent advances in the understanding of the mechanisms by which the low FODMAP diet impacts on symptoms in IBS recent evidence for its efficacy current findings regarding the consequences of the diet on the microbiome and recommendations for areas for future research. irritable bowel syndrome. intestinal microbiology.
Get PriceInnovations in Mixed Methods Evaluations Annual Review
Mixed methods research—i.e. research that draws on both qualitative and quantitative methods in varying configurations—is well suited to address the increasing complexity of public health problems and their solutions. This review focuses specifically on innovations in mixed methods evaluations of intervention program or policy (i.e. practice) effectiveness and implementation. The
Get PriceComparative Effectiveness Research American Academy of
Comparative effectiveness research is defined by the Institute of Medicine as "the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent diagnose treat and monitor a clinical condition or to improve the delivery of care.". •.
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Recent advances in endovascular and surgical techniques as well as clinical study results on comparative treatment methods strengthened the need for a comprehensive review of the published evidence for diagnosis management and prevention of PAD.
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Jul 16 2019 · Product anthropomorphism or imbuing products with human-like characteristics has been widely used in marketing practice (Aggarwal and McGill 2017 Kim Chen and Zhang 2016).Marketers may design an anthropomorphized visual representation of the product with human physical features (e.g. Jean Paul Gaultier designs perfume bottles with human body shapes) verbally describe the
Get PriceAntibody–Drug Conjugates A Comprehensive Review
Antibody–drug conjugates (ADC) are one of the fastest growing anticancer drugs. This approach comprises a mAb conjugated to the cytotoxic payload via a chemical linker that directed toward a target antigen expressed on the cancer cell surface reducing systemic exposure and therefore toxicity. ADCs are complex molecules that require careful attention to various components.
Get PriceEpithelialization in Wound Healing A Comprehensive Review
Recent advances in high-throughput sequencing technologies have facilitated studies of the complex microbial inhabitants of the human body by providing a more comprehensive identification of microbes than traditional culture methods. 143 These novel methods use 16S rRNA gene-based analyses to characterize the diversity of microbial communities
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In recent decades research about survey questions has emphasized decision-based approaches. Current research focuses on identifying and systematizing characteristics of questions that are key in researchers decisions. We describe important classes of decisions and question characteristics topic type of question (e.g. event or behavior evaluation or judgment) response dimension (e.g
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Jan 20 2021 · The field of microbiome research has progressed rapidly in recent years driven by technological advances and reduced costs of analysis .Significant insights have been made into the nature of microbial communities and their impact on host health .However there are inherent challenges and complexities in defining the boundary of a healthy microbiome landscape .
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The milling process is one of the most used processes in the manufacturing industry. Milling as a process as evolved with new machines and methods being employed in order to obtain the best results consistently. Milling tools have also seen quite an evolution from the uncoated high-speed steel tool to the now vastly used coated tools. Information on the use of these coated tools in
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Feb 01 2020 · Hydrogen production methods are reviewed and major challenges and recent advances are discussed. • Thermochemical cycles for H 2 production including pure and hybrid cycles are reviewed and discussed.. A comparative evaluation is performed for cycle s efficiency cost and environmental impact.
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Dec 21 2020 · Nanocorr drops a long read when there is no short read aligning to it. This procedure can remove many error-prone long reads which leads to a higher alignment identity after correction. However the fraction of discarded reads in many cases is found to be significant.
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Global developmental delay and intellectual disability are relatively common pediatric conditions. This report describes the recommended clinical genetics diagnostic approach. The report is based on a review of published reports most consisting of medium to large case series of diagnostic tests used and the proportion of those that led to a diagnosis in such patients.
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In this review recent advances in the field of multivalued logic gates based on emerging materials to provide a comprehensive guideline for possible future research directions are reviewed. First an overview of the design criteria and figures of merit for multivalued logic gates is presented and then advancements in various emerging
Get PriceComprehensive Evaluation of the Child With Intellectual
Global developmental delay and intellectual disability are relatively common pediatric conditions. This report describes the recommended clinical genetics diagnostic approach. The report is based on a review of published reports most consisting of medium to large case series of diagnostic tests used and the proportion of those that led to a diagnosis in such patients.
Get Price(PDF) THE IMPACT OF EMPLOYEE TRAINING AND DEVELOPMENT
An extensive review of the literature in terms of research findings from studies that have been trying to measure and understand the impact that individual HR practices like training have on
Get Price(PDF) Psoriasis A Review of Existing Therapies and Recent
Abstract. Psoriasis is a chronic autoimmune and non-communicable inflammatory disease of skin and joints. Antigen presenting cells activate naïve T cells which further differentiate into Th1
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Oct 26 2020 · Introduction. Over the past decade considerable advances have been made in the surveillance diagnosis and management of hepatocellular carcinoma.1 Despite decreasing incidence rates of the disease disease specific mortality rates remain high 2 and early diagnosis is vital to improving outcomes.3 4 Surveillance of hepatocellular carcinoma is an excellent method to detect the
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Recent advances in functional myocardial imaging including tissue Doppler echocardiography and strain echocardiography have also suggested that exercise training may lead to changes in LV systolic function that are not detected by assessment of a global index like LV ejection fraction. 4345 The importance of these findings with respect
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In an impact evaluation the focus will be on explaining how the programme contributed to observed outcomes and this will necessarily involve iterative description interpretation and explanation. Hence there will be a strong emphasis in an impact evaluation on synthesizing similarities and differences within and across cases and contexts. 2.
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Apr 06 2020 · A recent comparative study of a comprehensive dataset of 20 000 labelled human missense variants showed that Rhapsody outperformed EVmutation which in turn yielded more accurate predictions than PolyPhen-2 although the coverage of the latter was much wider since multiple sequence alignment data from Pfam was unnecessary. For this particular
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A comprehensive review of the pathophysiology clinical presentation and management of euglycemic ketoacidosis. 37 . Peacock SC Lovshin JA Cherney DZ. Perioperative considerations for the use of sodium-glucose cotransporter-2 inhibitors in patients with
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